E etsa joaloPRPsebetsa hantle?
01. Liphetho tsa liente tsa PRP sefahlehong
Botsofali ba letlalo la motho ka lebaka la ho putlama ha collagen le elastin ka tlas'a letlalo.Tšenyo ena e bonahala ka mokhoa oa mela e metle, wrinkles le creases phatleng, likhutlong tsa mahlo, pakeng tsa lintši le ho pota-pota molomo.U ka boela ua hlokomela li-creases mahetleng.Phello ena e etsahala ha botšepehi ba sebopeho sa likhoele tsa collagen bo senyeha ka lebaka la mabaka a ka hare le a ka ntle.Lintho tse phahameng tsa ho hōla ha sefahleho sa PRP li lokisa collagen le ho etsa hore fibroblasts e sebetse, e tsosolosa letlalo le ho tsosolosa ponahalo ea eona ea bocha.
02. Pele le Ka morao ho Phekolo ea Moriri oa PRP
Ho hlahloba katleho ea PRP bakeng sa tahlehelo ea moriri, lingaka li ile tsa etsa tlhahlobo ea ho hlotha moriri sehlopheng se sa reroang sa bakuli.Ba tšoara moriri o ka bang 50 ho isa ho 60 ebe ba o hulanya ho tloha hloohong.Pele ho kalafo, bakuli ba bangata ba ile ba lahleheloa ke moriri o ka bang 10.Pheta teko ea ho hula moriri ka mor'a liboka tse 'nè tsa PRP libeke tse 6 tse arohaneng.Bakuli ba tlalehile phokotso e kholo ea tahlehelo ea moriri ka likhoele tsa 3 feela tse arohaneng le letlalo la hlooho.Ho phaella moo, ngaka e tšoaea karolo e itseng ea letlalo la hlooho bakeng sa tlhahlobo.PRP pele le ka mor'a tlhahlobo e ile ea bontša ka li-follicle tsa moriri oa 71 le tse fetang 93 tsa moriri sebakeng seo, ka ho latellana.
03. Liphetho tsa Ente ea Knee ea PRP
Lingaka li hlahloba sehlopha sa bakuli ba osteoarthritis e netefalitsoeng ke MRI.Mokuli e mong le e mong o ile a fumana ente e le 'ngoe kapa tse peli tsa lengole la PRP tlas'a patella.Lingaka li lekola boemo ba bona ka nako ea libeke tse 6, likhoeli tse 3 le likhoeli tse 6.Ba fumane hore bakuli ba ne ba e-na le bohloko bo fokolang haholo le ho tsamaea hantle nakong ea libeke tsa 6 ho ea ho nako ea khoeli ea 3.Mosebetsi oa lengole o boetse oa ntlafala haholo.Likhoeli tse tšeletseng hamorao, liphello li ne li le betere ho feta pele ho opereishene, le hoja maemo a bohloko le mosebetsi a ne a sa ntlafala ho feta.
04. Tlhahlobo ea PRP bakeng saMakhopho a Makhophole Matshwao
nyeoe ea rona
PRP bakeng sa kalafo ea makhopho a letlalo
Tsoa!Mohlomphehi oa makhopho
Ho itšetlehile ka ho teba ha lehloba le tšenyo eo le e bakileng letlalong, maqeba a makhopho a ka hlaha ka mefuta e sa tšoaneng, e kang box car, ice pick le rolling car.Ho kenya PRP ho fihlela ho 1 mm ka tlase ho lebali ho ka thusa ho felisa maqeba a makhopho ka ho sa feleng.Haeba ho hlokahala, ngaka e ka ’na ea sebelisa linale tse ntle ho pshatla lebali le thata le keloid lebaling e le hore li ka arabela hamolemo kalafong.
Microneedling ke mokhoa o mong o sebelisoang ho fana ka serum letlalong.Lintlha tsa kholo ho PRP serum li lokisa lera la collagen tlas'a letlalo.Letlalo le fumana ponahalo ea molumo o lekanang kaha lera lena le hlahisa lisele tse ncha 'me le phalla libeke tse 4 ho isa ho tse 6.Meriana ea ho latela kamehla e ka thusa ho tsosolosa letlalo.
05. Litlhahlobo tsa Phekolo ea PRP bakeng sa Likotsi tsa Tendon
Hangata baatlelete ba na le likotsi tsa lithapo tsa setsoe, likotsi tsa rotator cuff, le meokho ea Achilles (joalo ka libapali tsa tennis le limathi).Ho ruruha ha tendon ea patellar sebakeng sa lengole ke kotsi e 'ngoe e tloaelehileng.Ho phaella ho mefuta e fapaneng ea bohloko, baatlelete ba fumana ho ruruha, ho thatafalloa ke ho sisinyeha, le ho utloahala ha molumo ha ba tsamaisa lenonyeletso le amehileng.
Liente tsa PRP tsa kotsi tsa lipapali tse behiloeng sebakeng se amehileng li ka thusa ho folisa likotsi tse ncha le tse sa foleng.Ka mor'a beke ea ho ruruha ho eketsehileng hang ka mor'a ente ea PRP, mokuli o ile a hlokomela ntlafatso ea butle-butle libeke tse latelang tsa 5.Ka ho phekola lisele tse thata tse thata, serum ea PRP e ka potlakisa pholiso.Ka lebaka leo, bohloko le ho ruruha li fokotseha hammoho le ho ntlafatsa ho tsamaea.
06. Liente tsa PRP bakeng sa likotsi tsa ligament le mesifa
Ho itšetlehile ka hore na ke mesifa efe e khethehileng eo ba e sebelisang khafetsa nakong ea papali ea bona, baatlelete ba litsebi ba ka bona likotsi tsa ligament, mesifa le lisele tse sebetsang.Mangole le lirope le li-sprains, hammoho le li-hamstrings tse tsitsitsoeng, hangata li baka ho ruruha le bothata ba ho tsamaea.Ho kenya PRP ka har'a mesifa e amehileng ho ka thusa ho potlakisa pholiso.Ka tsela ena, baatlelete ba ka khutsufatsa nako ea ho hlaphoheloa 'me ba khutlela lebaleng ka potlako.Lingaka tse ileng tsa etsa PRP pele le ka mor'a ho hlahlojoa li bontšitse pholiso ea bohlokoa ea maqeba.
07. Litlhahlobo tsa Liente tsa PRP Bakeng sa ho hloka thari
Boithuto bona bo entsoe ho sehlopha sa basali ba kaholimo ho lilemo tse 40. Maiteko a nakong e fetileng a ho ba thusa ho ima ka ho kenya mahe a emolisitsoeng a IVF a ile a hlōleha hobane lera la pōpelo le ne le se le teteaneng ka ho lekaneng.Boemo bona bo thibela ho kenngoa ha pōpelo ho kena ka popelong 'me ho ka baka ho senyeheloa ke mpa.Ka thuso ea motsoako oa liente tsa PRP le li-hormone tse tlatsetsang, lingaka li khona ho susumetsa tsoelo-pele ea lera la popelo.
Kalafo ea PRP e thusa ho fihlela boima bo nepahetseng ba 7mm ho isa ho 8mm kahoo basali ba khona ho jara boimana ba bona ho fihlela nako e telele.Liente tsa PRP bakeng sa ho hloka thari li ka boela tsa thusa ho lokisa mae a bomme le popelo ho basali ba bacha, ho ba lumella ho hlahisa le ho lokolla mahe a phetseng hantle.Lingaka li ile tsa kotula mahe 'me tsa a lokisetsa ho kenngoa ha IVF, e leng se ileng sa fella ka ho tsoaloa ha lesea le phelang hantle.
08. PRPdidikadikwe tse lefifipele le ka morao
Botsofali, maemo a tikoloho, ho hloka boroko le ho kula kaofela li ka kenya letsoho ho thehoeng ha li-circles tse lefifi le mahlo a puffy.Bakuli ba ka boela ba hlokomela letlalo le hlephileng ka tlas'a mahlo kapa se bonahalang eka ke mokelikeli ka mekotleng ea mahlo.Liente tsa PRP li ka thusa maemong ana kaofela ka ho theha methapo e mecha ea mali letlalong le boreleli.Methapo ena ea mali e fepa sebaka seo ka oksijene e ncha le limatlafatsi 'me e tlosa mokelikeli o bokeletsoeng, chefo le litšila.
Liphetho tsena tsa pele le ka morao ho PRP li bontša ka ho hlaka hore bofokoli ba letlalo bo kang hyperpigmentation, wrinkles le letlalo le saggy kaofela li nyametse, li senola mahlo a phatsimang.PRP e boetse e tsosolosa likarolo tsa collagen le elastin letlalong, ho tsosolosa ho tiea ha eona.
Pele le Ka mor'a PRP
Tsena pele le ka morao litšoantšo tsa liente tsa PRP li bontša ka ho hlaka hore ha phekolo ea PRP e etsoa ke ngaka e tiisitsoeng ke setsebi, e na le monyetla oa ho thusa batho ba nang le maemo a sa tšoaneng a meriana le a litlolo.Ho phaella ho maemo a ka holimo, PRP e tsejoa ho thusa ho folisa maqeba, ho thehoa ha masapo le ho kenngoa ha meno ka katleho tlhokomelong ea meno esita le ho buuoa ka pelo e bulehileng.Lilemong tse tlang, phekolo ea PRP e ka 'na ea boela ea e-ba le litataiso tse ling tse fapaneng tsa kliniki bakeng sa tšebeliso ea plasma e nang le platelet-rich (PRP) ho masapo a masapo ho khothalletsa ho lokisoa ha masapo.
Ho robeha ke ho khutlisetsoa morao ha ho tšepahala kapa ho tsoela pele ha lesapo.Ho robeha ho sa foleng ka mor'a likhoeli tse 9 'me ho sa bontše matšoao a ho fola nakong ea likhoeli tse 3 ho bitsoa "nonunion".Ho na le mabaka a mangata a ho lieha ho kopana ha fracture kapa ho se kopane, joalo ka bokooa ba masapo, tšoaetso, khaello ea phepo e nepahetseng, ho tsitsisa ho sa tsitsang, le ho senyeha ha phano ea mali kutung.
Ho na le mabaka a mangata a kotsi bakeng sa fractures ka nako e telele ea lefu, ho lieha ho kopana kapa ho se kopane, 'me phekolo e thata.Ho lieha ho kopana kapa ho se kopane ha fractures ho hlahisa bohloko, ho lahleheloa ke mosebetsi, le ho sotha maikutlong, ho bakang ho fokotseha ha boleng ba bophelo, ho sitoa ho sebetsa le ho fokotsa chelete e kenang ho bakuli.Fumana mabaka a kotsi a ho lieha ho fola kapele kamoo ho ka khonehang, fana ka ts'ebetso e nakong, 'me u fokotse litšenyehelo tsa bongaka.Liphuputso li bonts'itse hore ho tsuba le lefu la tsoekere ke mabaka a kotsi bakeng sa ho lieha ho kopana ha fracture, 'me tšebeliso ea li-nonsteroidal anti-inflammatory drugs (NSAIDs) le eona e ka baka ho lieha ho kopana ha fracture.Ho phaella moo, kotsi ea lisele tse bonolo le lefu la vascular le lebisa ho mathata a ho robeha, ho eketsa kotsi ea ho lieha ho kopana kapa ho se kopane.
Tšebeliso ea platelet rich plasma (PRP) e ntlafatsa phello ea phekolo ea pholiso ea fracture.PRP e tsoa mali a autologous a feletseng, a sebetsoang ka in vitro ho etsa tokisetso e nang le platelet e tsepamisitsoeng, e nang le mefuta e sa tšoaneng ea ho hōla e hlahisoang nakong ea tokiso ea tlhaho ea tšenyo ea masapo.Liphuputso li bontšitse hore PRP e na le phello ea ho khothalletsa osteogenesis, e ka khothalletsang pholiso le ho lokisoa ha fractures, bokooa ba masapo, nonunion, osteonecrosis, osteoporosis, ho senyeha ha mokokotlo, tšoaetso ea masapo le ho senya osteogenesis.Litaelo tsa boikoetliso ba tleliniki ke sesebelisoa se molemo ka ho fetisisa bakeng sa baoki le bakuli ho etsa liqeto tsa bongaka, ka sepheo sa ho qetela sa tlhahlobo e nepahetseng, e utloahalang le e sebetsang ea kalafo ea mafu.Ka lipatlisiso tse ntseng li eketseha le ts'ebeliso ea PRP lefapheng la masapo a masapo, bopaki bo bocha ba bongaka bo thehiloeng bopaking bo hlahisitsoe lilemong tsa morao tjena.E le ho laola hantle ho sebelisoa ha PRP ho lingaka tsa masapo, tataiso ena e ile ea thehoa ho latela bopaki ba hona joale.
ho lokisa lesapo
Pholiso ea fracture le tokiso ea lisele tsa lesapo li kenyelletsa mekhahlelo e 'meli:
Mokhahlelo oa pele ke mohato oa pele oa anabolic, o khetholloang ka ho thaothoa le ho aroloa ha lisele tsa stem ho theha methapo ea masapo le mali, le ho thehoa ha lefufuru.
Karolo ea bobeli ke karolo ea catabolic, e khetholloang ke ho tsosolosoa ha lefufuru ha e ntse e sebetsa e le setšoantšo sa ho thehoa ha lesapo le lecha ho nka sebaka sa lefufuru.Ka mor'a moo, lisele tsa callus li tsosolosoa 'me lesapo le sa tsoa thehoa le tsosolosoa ho ba cortical bone in situ.
Kakaretso ea ho folisa ke phello ea likokoana-hloko ea lisele tse amanang le lisele le pontšo ka har'a lisele tse nchafatsang.Nakong ea pele ea kotsi ea ho robeha, lisele tsa sebakeng seo li hlahisa lintho tse phelang, tse sebetsang e le manģosa a sebakeng seo le a tsamaiso nakong ea pholiso ea masapo, 'me a na le phello ea ho khothalletsa pholiso ea fracture.Ho se tloaelehe ha lintho tsena tsa tlhaho ho ka lebisa pholisong e sa tloaelehang ea masapo.
Ntlha ea kholo ea PRP
Phello ea ho lokisa masapo ea platelet concentrate e ka 'na ea bakoa ke lintlha tsa khōlo ea osteogenic eo e nang le eona.Ka mor'a hore li-platelet tse ka har'a li-platelet tse tebileng li sebelisoe ke k'halsiamo le / kapa prothrombin, platelet alpha granules e lokolla lintlha tse sa tšoaneng tsa kgolo ka exocytosis, tse kang vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), e fetolang kholo- β. (TGF-β), insulin-like growth factor (IGF), epidermal growth factor (EGF), joalo-joalo, lintlha tsena kaofela li na le liphello tsa osteogenic.
vascular endothelial growth factor
E ka tšehetsa le ho hokahanya sebopeho sa pele sa methapo ea mali le mehaho e meng ka ho laola ho falla, ho ata le ho arola lisele tsa vascular endothelial.Ka nako e ts'oanang, e ka etsa hore ho be le phapang ea li-osteoblasts 'me ke ntlha ea bohlokoa ea khōlo ea ho lokisa masapo.
platelet derived growth factor
Li-platelet tse kopantsoeng ho tloha lipheletsong tsa ho robeha li hlahisoa ka bongata 'me li tsoela pele ho hlahisoa haholo nakong eohle ea ho fola.Li ka laola ho falla le ho ata ha lisele tsa stem, le ho khothalletsa ho ata le ho arohana ha li-osteoblasts.
fetolang kholo factor-beta
E ka susumetsa chemotaxis le mitosis ea fibroblasts le osteoblasts, ea laola kholo ea lisele le ho ata ha li-osteoblasts, ea susumetsa motsoako oa masapo, ea lokisa matrix a extracellular, le ho khothalletsa pholiso ea masapo.Ho fokotseha ha TGF-β ho ka amahanngoa le ho lieha ha masapo kapa ho se kopane.
hormone ea ho hōla
(Hormone ea ho hōla, GH) / insulin-like growth factor-1 (IGF-1) e amahanngoa le ho lieha ho kopana ha masapo kapa ho se kopane, 'me ba kenya letsoho ho ata ha lisele tsa mesenchymal stem, lisele tsa periosteal, chondrocytes, osteoblasts, le osteoclasts le phapang. , ho laola ho thehoa ha masapo, ho susumetsa li-osteoblasts le li-chondrocyte ho hlahisa vascular endothelial growth factor, le ho khothalletsa angiogenesis.
Liphello tse khahlanong le ho ruruha tsa PRP
Li-leukocyte ka har'a liplatelete tse koalehileng li etsa hore nuclear factor kB (nuclear factor kappa B, NF-kB) e bontše ho tsoela pele ho matlafatsa karabelo ea ho ruruha tlas'a ketso ea fibroblasts le osteoblasts.TNF-α, e le cytokine ea bohlokoa ea karabo ea ho ruruha, e ka susumelletsa ho lokolloa ha TGF-β.TGF-β e na le ts'ebetso ea immunostimulatory nakong ea pele ea ho ruruha kapa ka khatello e tlaase, 'me e ka bokella lisele tsa ho ruruha;ka khatello e phahameng, e ka thibela kholo le mosebetsi oa lisele tsa ho ruruha tse kang T, B lymphocyte le macrophages, le ho thibela lisele tsa T tsa cytotoxic.Sireletsa 'mele tlhaselong ea' mele oa ho itšireletsa mafung 'me u thibele karabo ea ho ruruha.
Phello e khahlanong le tšoaetso ea PRP
Tšusumetso e khahlanong le tšoaetso ea platelet concentrate e thehiloe haholo-holo ho liplatelete le lisele tse tšoeu tsa mali tseo e nang le tsona.Liplatelete tse ka har'a liplatelete tse koaletsoeng li hlahisa li-peptide tse thibelang likokoana-hloko, tse ka senyang lisele tsa baktheria, li thibela motsoako oa likokoana-hloko tsa RNA, motsoako oa protheine kapa ho mena ha protheine, li thibela chefo ea baktheria, li kenya tšebetsong tsamaiso ea baktheria ea autolysis, ebe li fana ka liphello tsa antibacterial.Li-leukocyte li ka hokahanya tšireletso ea lisele, ho kenya tšebetsong li-neutrophils, le ho kenya likokoana-hloko tsa pathogenic ka li-cytokine tse fapaneng le liprotheine tsa likokoana-hloko.Boithuto bo bontšitse hore liplatelete tse tsepamisitsoeng tse nang le palo e kholo ea lisele tse tšoeu tsa mali li ka fokotsa sekhahla sa Staphylococcus aureus.Liteko tsa antibacterial in vitro li bontšitse hore PPR e na le liphello tsa antibacterial ho Staphylococcus aureus, Escherichia coli, Streptococcus agalactiae, le Shigella, empa ha ea ka ea e-ba le phello ho Pseudomonas aeruginosa, Klebsiella pneumoniae le Serratia.Mali kaofela a ne a se na phello ea antibacteria ho libaktheria tse boletsoeng ka holimo.
ha re phethela
1. Ho kopanya liplatelete tse teteaneng ho ka potlakisa pholiso ea fracture le ho khutsufatsa nako ea ho lula sepetlele.
2. E ka potlakisa pholiso ea ho se kopane 'me ea khutsufatsa nako ea ho lula sepetlele.
3. Bakeng sa bakuli ba robehileng, ba nang le bokooa, le bokooa ba masapo, tšebeliso ea platelet concentrate e ke ke ea eketsa liketsahalo tse mpe, tse kang tšoaetso, bofubelu ba sebaka seo le ho ruruha.
4. Bakeng sa nonunion e tsitsitseng le e tsitsitseng ea atrophic, ente ea sebakeng sa platelet concentrate e ka fokotsa monyetla oa ho sebetsa hape.
5. Li-platelet tse tsepamisitsoeng li ka ’na tsa khothalletsa ho lokisoa ha ho tsuba, ho robeha ha lefu la tsoekere, ho robeha ha litho tse ling le ho holofala ha masapo.
6. Ha ho phekoloa ho robeha, li-nonunion, le bokooa ba masapo hammoho le tšoaetso, concentrate ea platelet e matlafalitsoeng ea leukocyte e ka ba molemo ho feta leukocyte e futsanehileng ea platelet.
Rea u amohela ho ikopanya le Amain technology Co,.;Ltd, ho u fa sete e feletseng ea moralo oa phekolo ea PRP, reagent ea PRP + PRP ea pokello ea mali.
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Amain Technology Co., Ltd.
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Sichuan Amain Technology Co., Ltd.
Nako ea poso: Mar-15-2023
