AMRDT001 Dengue Combo Rapid Test Cassette

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Igama lemveliso:AMRDT001 Dengue Combo Rapid Test Cassette

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Inombolo yoMzekelo:AMRDT001

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ICassette yeDengue Combo Test Cassette (iGazi Elipheleleyo/iSerum/Plasma) luvavanyo olukhawulezayo lwechromatographic immunoassay yokufumanisa umgangatho we-NS1 antigen kunye ne-IgG kunye ne-IgM ye-antibodies ye-Dengue virus egazini lomntu lonke, i-serum, okanye i-plasma njengoncedo ekuxilongweni kweDengue. usulelo.

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Iinkcukacha

AMRDT001 Dengue Combo Rapid Test Cassette

I-Dengue yi-flavivirus, isasazwa yi-Aedes aegypti kunye ne-Aedes albopictus mosquitoes.Isasazwa ngokubanzi kwiindawo ezishushu nezishushu zehlabathi,1 kwaye ibangela usulelo olufikelela kwi-100 lezigidi ngonyaka.2 Usulelo lwe-Classic Dengue lubonakala ngokuqalisa ngesiquphe ngumkhuhlane, intloko ebuhlungu ebuhlungu, i-myalgia, i-arthralgia kunye nerhashalala.Usulelo olusisiseko lweDengue lubangela ukuba izilwa-buhlungu ze-IgM zinyuke ziye kwinqanaba elibonakalayo kwiintsuku ezi-3 ukuya kwezi-5 emva kokuqala komkhuhlane.I-antibodies ye-IgM iqhubela phambili kwi-30 ukuya kwiintsuku ze-90. 3 Uninzi lwezigulane ze-Dengue kwimimandla ehlala kuyo zinosulelo lwesibini, i-4 ebangela amanqanaba aphezulu e-IgG antibodies ngaphambi okanye ngaxeshanye kunye nempendulo ye-IgM.5 Ngoko ke, ukufunyanwa kwe-anti-Dengue IgM ethile kunye Izilwa-buhlungu ze-IgG zinokunceda ukwahlula phakathi kosulelo olusisiseko nolwesibini.I-NS1 yenye yeeproteni ezisi-7 zeDengue Virus ekucingelwa ukuba zibandakanyeka kuphindaphindo lwentsholongwane.I-NS1 ikhona njenge-monomer kwifomu yayo engekavuthwa kodwa icutshungulwa ngokukhawuleza kwi-endoplasmic reticulum ukuze yenze i-dimer ezinzileyo.Inani elincinci le-NS1 lihlala lihambelana ne-intracellular organelles apho kucatshangelwa ukuba ibandakanyeka ekuphindaphindweni kwentsholongwane.Intsalela ye-NS1 ifunyanwa nokuba inxulumene ne-plasma inwebu okanye ikhuselwe njenge-hexadimer enyibilikayo.I-NS1 ibalulekile ekusebenzeni kwentsholongwane kodwa umsebenzi wayo ochanekileyo webhayoloji akwaziwa.Amajoni omzimba aphakanyiswe ekuphenduleni i-NS1 kusulelo lwentsholongwane inokunqumla kunye nee-antigens zomhlaba weseli kwiiseli ze-epithelial kunye neeplatelet kwaye oku kuye kwabandakanyeka kuphuhliso lwe-Dengue Hemorrhagic fever.

AMRDT001 Dengue Combo Rapid Test Cassette

I-Dengue IgG/IgM Rapid Test Cassette (Igazi Elipheleleyo/iSerum/Plasma) yimbrane esekelwe kwi-immunoassay esemgangathweni yokufumanisa izilwa-buhlungu zeDengue egazini, kwiserum, okanye kwiplasma.Olu vavanyo lunamacandelo amabini, icandelo le-IgG kunye necandelo le-IgM.Kwicandelo le-IgG, i-IgG echasene nomntu igqunywe kwindawo yovavanyo lwe-IgG.Ngexesha lokuvavanya, i-specimen iphendula kunye ne-Dengue antigen-coated particles kwi-cassette yovavanyo.Umxube emva koko ufudukela phezulu kwi-membrane yechromatographically nge-capillary action kwaye isabela nge-IgG echasene nomntu kwindawo yovavanyo lwe-IgG.Ukuba umzekelo uqulethe izilwa-buhlungu ze-IgG kwiDengue, umgca onemibala uya kuvela kummandla wovavanyo we-IgG.Kwicandelo le-IgM, i-IgM echasene nomntu igqunywe kwindawo yovavanyo lwe-IgM.Ngexesha lovavanyo, umzekelo uphendula nge-IgM echasene nomntu.I-Dengue IgM antibodies, ukuba ikhona kwi-specimen, isabela kunye ne-IgM echasene nomntu kunye ne-Dengue antigen-coated particles kwi-cassette yovavanyo, kwaye le ngqungquthela ibanjwe yi-IgM echasene nomntu, yenze umgca onemibala kwingingqi yovavanyo lwe-IgM. .Ke ngoko, ukuba lo mzekelo une-Dengue IgG antibodies, kuya kuvela umgca onemibala kwindawo yovavanyo lwe-IgG.Ukuba umzekelo uqulethe izilwa-buhlungu zeDengue IgM, umgca onemibala uya kuvela kummandla wovavanyo we-IgM.Ukuba lo mzekelo awuqulathanga izilwa-buhlungu zeDengue, akukho mgca mbala uya kuvela kuyo nayiphi na imimandla yovavanyo, ebonisa isiphumo esibi.Ukuze usebenze njengolawulo lwenkqubo, umgca onemibala uya kuhlala ubonakala kummandla wolawulo, obonisa ukuba umthamo ofanelekileyo we-specimen wongeziwe kwaye i-membrane wicking yenzeke.

AMRDT001 Dengue Combo Rapid Test Cassette

I-Dengue NS1 Rapid Test Cassette (Igazi Elipheleleyo/iSerum/Plasma) yimbrane esekelwe kwi-immunoassay esemgangathweni yokubhaqa iDengue NS1 antigen egazini, kwiserum, okanye kwiplasma.Ngexesha lovavanyo, umzekelo udibana ne-Dengue antibody-conjugate kwikhasethi yovavanyo.I-conjugate ye-antibody yeGolide iya kubophelela kwi-antigen yeDengue kwisampulu yesampuli eya kuthi ibophe nge-Anti-Dengue NS1 egqunywe kwi-membrane.Njengoko i-reagent ihamba kwi-membrane, i-antibody ye-Dengue NS1 kwi-membrane iya kubophelela i-antibody-antigen complex ebangela ukuba umgca opinki okhanyayo okanye omnyama wenze kwindawo yovavanyo lwenwebu yovavanyo.Ubukhulu bemigca buya kwahluka ngokuxhomekeke kubungakanani be-antigen ekhoyo kwisampulu.Ukubonakala komgca wepinki kummandla wokuvavanya kufuneka kuthathwe njengesiphumo esihle.【IZIFUNDO】Ikhasethi yeDengue IgG/IgM yoVavanyo oluKhawulezayo iqulethe iDengue antigen conjugated gold colloid particles, anti-human IgM, anti-human IgG eqatywe kwinwebu.I-Dengue NS1 Rapid Test Cassette iqulethe i-anti-Dengue Ag conjugated colloid particles, i-anti-Dengue Ag egqunywe kwi-membrane.

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