Ọnụ-arụmọrụ lepu COVID-19 antigen ngwa ngwa ule ngwa ngwa AMRPA77

Ọnụ ahịa lepu COVID-19 antigen ngwa ngwa ule ngwa ngwa AMRPA77 AMRPA77 Ezubere iji
Emebere ngwaahịa a maka nchọpụta qualitative nke antigen megide SARS-CoV-2 na nlele ụlọ ọgwụ (swab imi).

Ọnụ-arụmọrụ lepu COVID-19 antigen ngwa ngwa ule ngwa ngwa AMRPA77

Na-adịghị emerụ ahụ
Dị mfe iji
Ọ dị mma, enweghị ngwaọrụ achọrọ
Ngwa ngwa, nweta nsonaazụ n'ime nkeji iri na ise
Stable, na elu izi ezi
Dị ọnụ ala, ọnụ ahịa-arụmọrụ

Ọnụ-arụ ọrụ lepu COVID-19 antigen ngwa ngwa ule ngwa ngwa AMRPA77 Nchịkọta
Coronavirus, dị ka ezinụlọ nje buru ibu, bụ otu nje RNA dị mma nke nwere envelopu.A maara nje a na-ebute nnukwu ọrịa dịka oyi, Middle East Respiratory Syndrome (MERS), na Ọrịa siri ike iku ume (SARS).

Isi protein nke SARS-CoV-2 bụ protein N (Nucleocapsid), nke bụ akụkụ protein dị n'ime nje.A na-echekwa ya nke ọma n'etiti β-coronaviruses ma a na-ejikarị ya eme ihe maka nyocha nke coronaviruses.ACE2, dị ka isi ihe nnabata maka SARS-CoV-2 ịbanye na sel, dị oke mkpa maka nyocha nke usoro ọrịa nje.

Ọnụ-arụ ọrụ lepu COVID-19 antigen ngwa ule ngwa ngwa AMRPA77 Principle
Kaadị ule ugbu a dabere na mmeghachi omume antibody-antigen na teknụzụ immunoanalysis.Kaadị ule ahụ nwere ọla edo colloidal akpọrọ SARS-CoV-2 N protein monoclonal antibody nke kpuchiri ya na pad ngwakọta, dakọtara SARS-CoV-2 N protein monoclonal antibody na-anaghị emegharị ahụ na mpaghara ule (T) yana mgbochi kwekọrọ na mma. ebe njikwa (C).

N'oge nnwale, protein N dị na nlele ahụ na-ejikọta ya na ọla edo colloidal akpọrọ SARS-CoV-2 N protein monoclonal antibody nke kpuchiri ya na pad ngwakọta.Njikọ ndị ahụ na-akwaga n'elu n'okpuru mmetụta capillary, ma emesịa ejide ya site na N protein monoclonal antibody na-enweghị ike imegharị na mpaghara ule (T).

Ka ọdịnaya nke protein N dị na nlele ahụ dị elu, ka conjugates na-ejide ma na-agba ọchịchịrị na mpaghara ule ahụ.

Ọ bụrụ na enweghị nje na nlele ma ọ bụ ọdịnaya nje dị ala karịa njedebe nchọpụta, mgbe ahụ ọ nweghị agba gosipụtara na mpaghara ule (T).

N'agbanyeghị ọnụnọ ma ọ bụ enweghị nje na nlele ahụ, eriri na-acha odo odo ga-apụta na mpaghara njikwa mma (C).

Ụkwụ na-acha odo odo na mpaghara njikwa mma (C) bụ ihe nrịba ama maka ikpe ma ọ bụ na e nwere ihe nlele zuru ezu ma ọ bụ na usoro chromatography bụ ihe nkịtị.